Home
    About the Center
    Physical Activity
    Resources and Bibliography
    Aging Network
    Features
    Long Term Care Institute
    Contact Us
    Subscribe to NAN
 
Effect of Multivitamin and Mineral Supplementation on Episodes of Infection in Nursing Home Residents: A Randomized, Placebo-Controlled Study
  To evaluate the effect of vitamin and mineral supplementation on infections in an elderly institutionalized population. Outcome data from 748 subjects, mean age 85, were included in the intention-to-treat analysis. Using univariate analyses, there was no difference in infectious episodes between the supplemented and placebo groups (3.5 infections per 1,000 resident-days vs 3.8 infections per 1,000 resident-days, odds ratio (OR)=0.92, 95% confidence interval (CI)=0.821.03, P=.12). There was a reduction in antibiotic usage in the supplementation group, but this was not significant in the multivariate model. There was no difference in the number of hospital visits. In the multivariate analysis, the effect of multivitamin use on total number of infections was not significant (OR=0.77, 95% CI=0.541.1). Subjects without dementia had a greater rate of infections than those with dementia (OR=1.44, 95% CI=1.191.76). In post hoc subgroup analysis, subjects without dementia who received supplementation had a significantly lower rate of infections than those who received placebo (relative risk=0.81, 95% CI=0.660.99). Overall, multivitamin and mineral supplementation does not have a significant effect on the incidence of infections in institutionalized seniors, although the subgroup of residents in long-term care without dementia may benefit from supplementation. Further research is needed to determine its effect in high-risk subgroups within the nursing home population.
   
Type Journal - Bibliographic Record
Resource Type
(If applicable)
Author(s) Liu BA, McGeer A, McArthur MA, Dimor AE, Aghdassi E, Davis L, Allard JP
Book Publisher
Journal Publisher J Am Geriat Soc
Year 2007
Pages Page null
Article Title
Edition 55(1)
Contact Information
(If applicable)
Comments
(If applicable)
 
     »  Search Resource Center
       Type Keyword:

National Resource Center on Nutrition, Physical Activity & Aging
| Florida International University, OE 200, Miami, FL 33199
Phone: 305-348-1517 | Fax: 305-348-1518 | E-mail: nutrionandaging@fiu.edu


This website is supported, in part, by a grant from the Administration on Aging, Department of Health and Human
Services (DHHS). Grantees undertaking projects under government sponsorship are encouraged to express freely their
findings and conclusions. Points of view or opinions do not, therefore, reflect official DHHS policy.