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Prevalence and correlates of sleep-disordered breathing in older men: Osteoporotic Fractures in Men Sleep Study. |
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OBJECTIVES: To determine the prevalence and distribution of sleep-disordered breathing and associated correlates in a large cohort of older men using several standardized definitions.
DESIGN: Cross-sectional analyses.
SETTING: Six U.S. communities.
PARTICIPANTS: Polysomnography was performed on 2,911 participants of the Outcomes of Sleep Disorders in Older Men Sleep Study (mean age±standard deviation 76.38±5.53; body mass index 27.17±3.8 kg/m2).
MEASUREMENTS: Three outcomes were assessed: sleep-disordered breathing (respiratory disturbance index ≥15), obstructive apnea (obstructive apnea index ≥5), and central apnea (central apnea index ≥5).
RESULTS: The prevalence of moderate–severe sleep-disordered breathing was estimated to be 21.4% to 26.4%. Multivariable logistic regression models demonstrated that age (adjusted odds ratio (AOR) per 5-year increase =1.24, 95% confidence interval (CI)=1.15–1.34), obesity (AOR=2.54, 95% CI=2.09–3.09), Asian versus Caucasian race (AOR=2.14, 95% CI=1.33–3.45), snoring (AOR=2.01, 95% CI=1.62–2.49), sleepiness (AOR=1.41, 95% CI=1.11–1.79), hypertension (AOR=1.26, 95% CI=1.06–1.50), cardiovascular disease (AOR=1.24, 95% CI=1.19–1.29), and heart failure (AOR=1.81, 1.31–2.51) were independently associated with sleep-disordered breathing; snoring (AOR=2.10, 95% CI=1.67–2.70), age (AOR per 5-year increase=1.27, 95% CI=1.18–1.38), obesity (AOR=1.48, 95% CI=1.21–1.82), and heart failure (AOR=1.60, 95% CI=1.15–2.24) were associated with obstructive apnea; and age (AOR=1.33, 1.17–1.50) and heart failure (AOR=1.88, 95% CI=1.17–3.04) were associated with central apnea.
CONCLUSION: Regardless of definition, a high prevalence of sleep disorders is observed in community-dwelling older men. Qualitatively similar associations were observed between sleep disorders and snoring, obesity, and comorbidities, as reported for middle aged populations. Asian race was associated with sleep-disordered breathing.
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Journal - Bibliographic Record |
Resource Type
(If applicable)
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Mehra R, Stone KL, Blackwell T, Israel SA, Dam TL, Stefanick ML, Redline S, for the Osteoporotic Fractures in Men Study. |
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| Journal Publisher |
J Am Geriat Soc |
| Year |
2007 |
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N/A |
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Contact Information
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Comments
(If applicable)
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National Resource Center on Nutrition, Physical Activity & Aging | Florida International University, OE 200, Miami, FL 33199
Phone: 305-348-1517 | Fax: 305-348-1518 | E-mail: nutrionandaging@fiu.edu
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